Publications

31. Whitton AE, Webb CA, Dillon DG, Kayser J, Rutherford A, Goer F, Fava M, McGrath P, Weissman M, Parsey R, Adams P, Trombello JM, Cooper C, Deldin P, Oquendo MA, McInnis MG, Carmody T, Bruder G, Trivedi MH,  Pizzagalli DA. Pre-treatment rostral anterior cingulate cortex connectivity with salience network predicts depression recovery: Findings from the EMBARC randomized clinical trial. Biological Psychiatry. 2018 Dec [accepted].

30. Whitton AE, Green AI, Pizzagalli DA, Roth RM, Williams JM, Brunette MF. Potent dopamine D2 antagonists block the reward-enhancing effects of nicotine in smokers with schizophrenia. Schizophrenia Bulletin. 2018 Nov [accepted].

29. Finan PH, Whitton AE, Letzen JE, Remeniuk B, Robinson ML, Irwin MR, Pizzagalli DA, Smith MT. Experimental sleep disruption and reward learning: moderating role of positive affect responses. Sleep. 2018 Nov [accepted].

28. Tan A, Costi S, Lorris LS, Van Dam NT, Kautz M, Friedman AK, Collins KA, Ahle G, Chadha N, Whitton AE, Dunsky K, Do B, Pizzagalli DA, Iosifescu DV, Nestler EJ, Han M-H, Murrough JW. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular Psychiatry. 2018 Nov 1 [in press]. Link

27. Schneier FR, Slifstein M, Whitton AE, Pizzagalli DA, Reinen J, McGrath PJ, Iosifescu DV, Abi-Dargham A. Dopamine release in antidepressant-naïve major depressive disorder: a multimodal [11C]-(+)-PHNO positron emission tomography and functional magnetic resonance imaging study. Biological Psychiatry. 2018 May 25;84:563-573. Link

26. Whitton AE, Mehta M, Ironside ML, Murry G, Pizzagalli DA. Evidence for diurnal variation in implicit reward learning. Chronobiology International. 2018 Apr 24;35:1104-1114. Link

25. Sperl MFJ, Panitz C, Rosso IM, Dillon DG, Kumar P, Hermann A, Whitton AE, Hermann C, Pizzagalli DA, Mueller EM. Fear extinction recall modulates human frontomedial theta and amygdala activity. Cerebral Cortex. 2018 Jan 24 [in press]. Link

24. Kaiser RH, Treadway MT*, Wooten DW*, Kumar P*, Goer F, Murray L, Beltzer M, Pechtel P, Whitton AE, Cohen AL, Alpert NM, El Fakhri G, Normandin MD, Pizzagalli DA. Frontostriatal and dopamine markers of individual differences in reinforcement learning: A multi-modal investigation. Cerebral Cortex. 2017 Oct 31 [in press] *These authors made equal contributions. Link

23. Whitton AE, Deccy S, Ironside ML, Kumar P, Beltzer P, Pizzagalli DA. EEG source functional connectivity reveals abnormal high-frequency communication among large-scale functional networks in depression. Biological Psychiatry: Cognitive Neuroscience & Neuroimaging. 2017 Jul 12;3:50-58. Link

22. Nangle MR, Bailey PE, Henry JD, Khlentzos GS, Varcin KJ, Whitton AE. Age invariance in rapid facial affective reactions to emotionally valenced stimuli. Quarterly Journal of Experimental Psychology. 2017 June 18;71:1687-1698. Link

21. Whitton AE, Van’t Veer A, Kakani P, Dillon DG, Haile A, Crowley DJ, Pizzagalli DA. Acute stress impairs frontocingulate activation during error-monitoring in remitted depression. Psychoneuroendocrinology. 2017 Jan 31;75:164-174. Link

20. Lewandowski LE, Whitton AE, Pizzagalli DA, Norris L, Ongur D, Hall MH. Reward learning, neurocognition, social cognition, and symptomatology in psychosis. Frontiers in Psychiatry. 2016 Jun 14;7:a100. Link

19. Clarke J, Proudfoot J, Whitton AE, Birch M-R, Boyd MA, Parker G, Manicavasagar V, Fogarty A. Therapeutic alliance with a mobile phone and web intervention for depression, anxiety and stress: Secondary analysis of a randomized controlled trial using mixed methods. JMIR Mental Health. 2016 Jan 1;3:e10. Link

18. Whitton AE, Kakani P, Foti D, Van’t Veer A, Haile A, Crowley DJ, Pizzagalli DA.  Blunted neural responses to reward in remitted major depression: A high-density event-related potential study. Biological Psychiatry: Cognitive Neuroscience & Neuroimaging, 2016 Jan 31;1:87-95. Link

17. Peechatka AL, Whitton AE, Farmer SL, Pizzagalli DA, Janes AC. Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug & Alcohol Dependence. 2015 Oct 1;155:202-207. Link

16. Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson M, Huz I, Fava M, Pizzagalli DA, Evins AE. Reward responsiveness varies by smoking status in women with a history of major depressive disorder. Neuropsychopharmacology. 2015 Jul 1;40;1940-1946. Link

15. Whitton AE, Treadway MT, Pizzagalli DA. Reward processing dysfunction in major depression, bipolar disorder and schizophrenia. Current Opinion in Psychiatry. 2015 Jan 1;28:7-12. Link

14. Whitton AE, Proudfoot J, Clarke J, Birch M-R, Parker G, Manicavasagar V, Harrison V, Hadzi-Pavlovic D. Breaking open the black box: Isolating the most potent components of a web and mobile phone-based intervention for depression, anxiety and stress. JMIR Mental Health. 2015 Jan 1;2.1:e3. Link

13. Whitton AE, Henry JD, Grisham JR. Cognitive and psychophysiological correlates of disgust in obsessive-compulsive disorder. British Journal of Clinical Psychology. 2015 Mar 1;54:16-33. Link

12. Clarke J, Proudfoot J, Birch M-R, Whitton AE, Parker G, Manicavasagar V, Harrison V, Christensen H, Hadzi-Pavlovic D. Effects of mental health self-efficacy on outcomes of a mobile phone and web intervention for mild-to-moderate depression, anxiety and stress: Secondary analysis of a randomized controlled trial. BMC Psychiatry. 2014 Sep 26;14:272. Link

11. Grisham JR, Becker L, Williams AJ, Whitton AE, Makkar S. Using cognitive bias modification to deflate responsibility bias in compulsive checkers. Cognitive Therapy and Research. 2014 Oct 1;38:505-517. Link

10. Proudfoot J, Whitton AE, Parker G, Manicavasagar V, Nicholas J, Smith M. Evidence of a weekly cyclicity in mood and functional impairment in individuals with a bipolar disorder. Psychiatry Research. 2014 Aug 30;218:290-294. Link

9. Whitton AE, Henry JD, Rendell PG, Grisham JR. Disgust, but not anger provocation, enhances levator labii superioris activity during exposure to moral transgressions. Biological Psychology. 2014 Feb 28;96:48-56. Link

8. Whitton AE, Henry JD, Grisham JR. Moral rigidity in obsessive-compulsive disorder: Do abnormalities in inhibitory control, cognitive flexibility and disgust play a role? Journal of Behavior Therapy and Experimental Psychiatry. 2014 Mar 1;45:152-159. Link

7. Proudfoot J, Clarke J, Birch M-R, Whitton AE, Parker G, Manicavasagar V, Harrison V, Christensen H, Hadzi-Pavlovic D.  Impact of a mobile phone and web psychological program on depression, anxiety, stress, work and social functioning: A randomized controlled trial. BMC Psychiatry. 2013 Nov 18;13:312. Link

6. Whitton AE, Grisham JR, Henry JD, Palada HD. Interpretive bias modification for disgust. Journal of Experimental Psychopathology. 2013 Jul 21;4:341-359. Link

5. Whitton AE, Henry JD. The relationship between sub-clinical obsessive-compulsive symptoms and social cognition in chronic schizophrenia.  British Journal of Clinical Psychology. 2013 June 1;52:155-128. Link

4. Proudfoot J, Jayawant A, Whitton AE, Parker G, Manicavasagar V, Smith M., Nicholas J.  Mechanisms underpinning effective peer support: A qualitative analysis of interactions between expert peers and patients newly diagnosed with bipolar disorder. BMC Psychiatry. 2012 Nov 9;12:192. Link

3. Proudfoot J, Whitton AE, Parker G, Doran J, Manicavasagar V, Delmas K.  Triggers of mania and depression in young people with bipolar disorder.  Journal of Affective Disorders. 2012 Dec 20;143:196-202. Link

2. Proudfoot J, Parker G, Manicavasagar V, Hadzi-Pavlovic D, Whitton AE, Nicholas J, Smith M. Effects of adjunctive peer support on perceptions of illness control and understanding in an online psychoeducation program for bipolar disorder: A randomized controlled trial.  Journal of Affective Disorders. 2012 Dec 15;142:98-105. Link

1. Proudfoot J, Parker G, Hadzi-Pavlovic D, Manicavasagar V, Adler E, Whitton AE.  Community attitudes to the appropriation of mobile phones for monitoring and managing depression, anxiety and stress.  Journal of Medical Internet Research. 2010 Dec 19;12:e64. Link