46. Kumar P, Jiang S, Whitton AE. Brain imaging of reward dysfunction in unipolar and bipolar disorders. In: Selvaraj S, Brambilla P, Soares JC (Eds.) Mood Disorders: Brain Imaging and Therapeutic Implications. UK: Cambridge University Press; 2021, pp.39-48. Link

45. Whitton AE, Kumar P, Treadway MT, Rutherford AV, Ironside ML, Foti D, Fitzmaurice G, Du F, Pizzagalli DA. Mapping disease course across the mood disorder spectrum through a Research Domain Criteria (RDoC) framework. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2021 Jan 26 [Epub ahead of print]. Link

44. Parker BL, Chackouch C, Subotic-Kerry M, Batterham P, Mackinnon A, Newby JM, Whitton AE, McGoldrick J, Cockayne N, O’Dea B. A cluster ransomised controlled trial of the Building Edicators’ Skills in Adolescent Mental Health (BEAM) training program: Trial protocol. JMIR Research Protocols. [Accepted 22 Jan 2021].

43. Shaw SR, El-Omar H, Roquet D, Hodges JR, Piguet O, Ahmed RM, Whitton AE, Irish M. Adopting a transdiagnostic approach to determine the the prevalence and neural substrates of anhedonia in frontotemporal dementia. Brain. [Accepted 30 Nov 2020].

42. Costi S, Morris LS, Kirkwood KA, Hoch M, Corniquel M, Vo-Le B, Iqbal T, Chadha N, Pizzagalli DA,  Whitton AE,  Bevilacqua L,  Jha MK, Ursu S, Swann AC,  Collins KA, Salas R, Bagiella E, Parides MK, Stern ER, Iosifescu DV,  Han M-H, Mathew SJ, Murrough JW. Impact of the KCNQ2/3 channel opener ezogabine on reward circuit activity and clinical symptoms in depression: results from a randomized controlled trial. American Journal of Psychiatry. [Accepted 21 Oct 2020]. doi: 10.1176/appi.ajp.2020.20050653

41. Whitton AE, Merchant, J, Lewandowski, KE. Dissociable mechanisms underpinning effort-cost decision-making across the psychosis spectrum. Schizophrenia Research. 2020 Oct 9 [ePub ahead of print] Published articleFree full text article

40. Reilly EE, Whitton AE, Pizzagalli DA, Rutherford AV, Stein MB, Paulus MP, Taylor CT. Diagnostic and dimensional evaluation of implicit reward learning in social anxiety disorder and major depression. Depression & Anxiety. 2020 Sep 9 [ePub ahead of print]. Link

39. Pizzagalli DA, Smoski M, Ang Y-S, Whitton AE, Sanacora G, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu DV, Murrough JW, Yang H, Weiner RD, Calabrese JR, Goodman W, Potter WZ, Krystal AD. Selective kappa opioid antagonism ameliorates anhedonic behavior: Evidence from the Fast-Fail Trial in mood and anxiety spectrum disorders (FAST-MAS). Neuropsychopharmacology. 2020 Jun 16;45:1656–1663. Link

38. Murphy M, Whitton AE, Deccy S, Ironside ML, Rutherford A, Beltzer M, Sacchet M, Pizzagalli DA. Abnormalities in electroencephalographic microstates are state and trait markers of major depressive disorder. Neuropsychopharmacology. 2020 Jun 26 [ePub ahead of print]. Link

37. Carpenter JS, Iorfino F, Cross SPM, Nichles A, Zmicerevska N, Hoyos Lopez V, Groot J, Crouse JJ, Palmer J, Whitton AE, White D, Naismith SL, Guastella A, Hermens DF, Scott J, Scott EM, Hickie IB. Protocol for the Brain and Mind Centre Optymise Cohort: Tracking multi-dimensional outcomes in young people presenting for mental health care. BMJ Open. 2020 Mar 1;10: e030985. Link

36. Krystal AD, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Calabrese JR, Sanacora G, Hermes G, Keefe RSE, Song A, Goodman W, Szabo ST, Whitton AE, Gao K,  Potter WZ. Application of the “Fast-Fail” approach to evaluating the potential of selective Kappa Opioid Antagonism as a treatment for anhedonia: A randomized proof of mechanism trial assessing effects on the ventral striatum. Nature Medicine. 2020 Mar 30;26:760-768. Link

35. Whitton AE, Reinen JM, Slifstein M, Ang Y-S, McGrath PJ, Iosifescu DV, Abi-Dargham A, Pizzagalli DA, Schneier FR. Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain. 2020 Feb 10;143:701-710. Published article; Free full text article

34. Whitton AE, Webb CA, Dillon DG, Kayser J, Rutherford A, Goer F, Fava M, McGrath P, Weissman M, Parsey R, Adams P, Trombello JM, Cooper C, Deldin P, Oquendo MA, McInnis MG, Carmody T, Bruder G, Trivedi MH,  Pizzagalli DA. Pre-treatment rostral anterior cingulate cortex connectivity with salience network predicts depression recovery: Findings from the EMBARC randomized clinical trial. Biological Psychiatry. 2019 May 15;85:872-880. Link

33. Whitton AE, Treadway MT, Ironside ML, Pizzagalli DA. Neurobiological Reward-Related Abnormalities Across Mood Disorders. In: The Oxford Handbook of Positive Emotion and Psychopathology 2019 (pp. 223-238). Oxford University Press. Link

32. Whitton AE, Lewandowski KE. Reward processing and social functioning in psychosis. In: Social Cognition in Psychosis 2019 (pp. 177-200). Academic Press. Link

31. Finan PH, Whitton AE, Letzen JE, Remeniuk B, Robinson ML, Irwin MR, Pizzagalli DA, Smith MT. Experimental sleep disruption and reward learning: moderating role of positive affect responses. Sleep. 2019 May 1;42:zsz026. Link

30. Sperl MFJ, Panitz C, Rosso IM, Dillon DG, Kumar P, Hermann A, Whitton AE, Hermann C, Pizzagalli DA, Mueller EM. Fear extinction recall modulates human frontomedial theta and amygdala activity. Cerebral Cortex. 2019 Feb 1;29:701-715. Link

29. Whitton AE, Green AI, Pizzagalli DA, Roth RM, Williams JM, Brunette MF. Potent dopamine D2 antagonists block the reward-enhancing effects of nicotine in smokers with schizophrenia. Schizophrenia Bulletin. 2019 Oct 24;45:1300-1308. Link

28. Kaiser RH, Treadway MT*, Wooten DW*, Kumar P*, Goer F, Murray L, Beltzer M, Pechtel P, Whitton AE, Cohen AL, Alpert NM, El Fakhri G, Normandin MD, Pizzagalli DA. Frontostriatal and dopamine markers of individual differences in reinforcement learning: A multi-modal investigation. Cerebral Cortex. 2018 Dec 1;28:4281-4290. *These authors made equal contributions. Link

27. Tan A, Costi S, Lorris LS, Van Dam NT, Kautz M, Friedman AK, Collins KA, Ahle G, Chadha N, Whitton AE, Dunsky K, Do B, Pizzagalli DA, Iosifescu DV, Nestler EJ, Han M-H, Murrough JW. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular Psychiatry. 2018 Nov 1 [in press]. Link

26. Pizzagalli DA, Whitton AE, Webb CA. Mood disorders. In: APA handbook of psychopathology: Psychopathology: Understanding, assessing, and treating adult mental disorders, Vol. 1 2018 (pp. 403-427). American Psychological Association. Link

25. Schneier FR, Slifstein M, Whitton AE, Pizzagalli DA, Reinen J, McGrath PJ, Iosifescu DV, Abi-Dargham A. Dopamine release in antidepressant-naïve major depressive disorder: a multimodal [11C]-(+)-PHNO positron emission tomography and functional magnetic resonance imaging study. Biological Psychiatry. 2018 May 25;84:563-573. Link

24. Whitton AE, Mehta M, Ironside ML, Murry G, Pizzagalli DA. Evidence for diurnal variation in implicit reward learning. Chronobiology International. 2018 Apr 24;35:1104-1114. Link

23. Whitton AE, Deccy S, Ironside ML, Kumar P, Beltzer P, Pizzagalli DA. EEG source functional connectivity reveals abnormal high-frequency communication among large-scale functional networks in depression. Biological Psychiatry: Cognitive Neuroscience & Neuroimaging. 2017 Jul 12;3:50-58. Link

22. Nangle MR, Bailey PE, Henry JD, Khlentzos GS, Varcin KJ, Whitton AE. Age invariance in rapid facial affective reactions to emotionally valenced stimuli. Quarterly Journal of Experimental Psychology. 2017 June 18;71:1687-1698. Link

21. Whitton AE, Van’t Veer A, Kakani P, Dillon DG, Haile A, Crowley DJ, Pizzagalli DA. Acute stress impairs frontocingulate activation during error-monitoring in remitted depression. Psychoneuroendocrinology. 2017 Jan 31;75:164-174. Link

20. Lewandowski LE, Whitton AE, Pizzagalli DA, Norris L, Ongur D, Hall MH. Reward learning, neurocognition, social cognition, and symptomatology in psychosis. Frontiers in Psychiatry. 2016 Jun 14;7:a100. Link

19. Clarke J, Proudfoot J, Whitton AE, Birch M-R, Boyd MA, Parker G, Manicavasagar V, Fogarty A. Therapeutic alliance with a mobile phone and web intervention for depression, anxiety and stress: Secondary analysis of a randomized controlled trial using mixed methods. JMIR Mental Health. 2016 Jan 1;3:e10. Link

18. Whitton AE, Kakani P, Foti D, Van’t Veer A, Haile A, Crowley DJ, Pizzagalli DA.  Blunted neural responses to reward in remitted major depression: A high-density event-related potential study. Biological Psychiatry: Cognitive Neuroscience & Neuroimaging, 2016 Jan 31;1:87-95. Link

17. Peechatka AL, Whitton AE, Farmer SL, Pizzagalli DA, Janes AC. Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug & Alcohol Dependence. 2015 Oct 1;155:202-207. Link

16. Janes AC, Pedrelli P, Whitton AE, Pechtel P, Douglas S, Martinson M, Huz I, Fava M, Pizzagalli DA, Evins AE. Reward responsiveness varies by smoking status in women with a history of major depressive disorder. Neuropsychopharmacology. 2015 Jul 1;40;1940-1946. Link

15. Whitton AE, Treadway MT, Pizzagalli DA. Reward processing dysfunction in major depression, bipolar disorder and schizophrenia. Current Opinion in Psychiatry. 2015 Jan 1;28:7-12. Link

14. Whitton AE, Proudfoot J, Clarke J, Birch M-R, Parker G, Manicavasagar V, Harrison V, Hadzi-Pavlovic D. Breaking open the black box: Isolating the most potent components of a web and mobile phone-based intervention for depression, anxiety and stress. JMIR Mental Health. 2015 Jan 1;2.1:e3. Link

13. Whitton AE, Henry JD, Grisham JR. Cognitive and psychophysiological correlates of disgust in obsessive-compulsive disorder. British Journal of Clinical Psychology. 2015 Mar 1;54:16-33. Link

12. Clarke J, Proudfoot J, Birch M-R, Whitton AE, Parker G, Manicavasagar V, Harrison V, Christensen H, Hadzi-Pavlovic D. Effects of mental health self-efficacy on outcomes of a mobile phone and web intervention for mild-to-moderate depression, anxiety and stress: Secondary analysis of a randomized controlled trial. BMC Psychiatry. 2014 Sep 26;14:272. Link

11. Grisham JR, Becker L, Williams AJ, Whitton AE, Makkar S. Using cognitive bias modification to deflate responsibility bias in compulsive checkers. Cognitive Therapy and Research. 2014 Oct 1;38:505-517. Link

10. Proudfoot J, Whitton AE, Parker G, Manicavasagar V, Nicholas J, Smith M. Evidence of a weekly cyclicity in mood and functional impairment in individuals with a bipolar disorder. Psychiatry Research. 2014 Aug 30;218:290-294. Link

9. Whitton AE, Henry JD, Rendell PG, Grisham JR. Disgust, but not anger provocation, enhances levator labii superioris activity during exposure to moral transgressions. Biological Psychology. 2014 Feb 28;96:48-56. Link

8. Whitton AE, Henry JD, Grisham JR. Moral rigidity in obsessive-compulsive disorder: Do abnormalities in inhibitory control, cognitive flexibility and disgust play a role? Journal of Behavior Therapy and Experimental Psychiatry. 2014 Mar 1;45:152-159. Link

7. Proudfoot J, Clarke J, Birch M-R, Whitton AE, Parker G, Manicavasagar V, Harrison V, Christensen H, Hadzi-Pavlovic D.  Impact of a mobile phone and web psychological program on depression, anxiety, stress, work and social functioning: A randomized controlled trial. BMC Psychiatry. 2013 Nov 18;13:312. Link

6. Whitton AE, Grisham JR, Henry JD, Palada HD. Interpretive bias modification for disgust. Journal of Experimental Psychopathology. 2013 Jul 21;4:341-359. Link

5. Whitton AE, Henry JD. The relationship between sub-clinical obsessive-compulsive symptoms and social cognition in chronic schizophrenia.  British Journal of Clinical Psychology. 2013 June 1;52:155-128. Link

4. Proudfoot J, Jayawant A, Whitton AE, Parker G, Manicavasagar V, Smith M., Nicholas J.  Mechanisms underpinning effective peer support: A qualitative analysis of interactions between expert peers and patients newly diagnosed with bipolar disorder. BMC Psychiatry. 2012 Nov 9;12:192. Link

3. Proudfoot J, Whitton AE, Parker G, Doran J, Manicavasagar V, Delmas K.  Triggers of mania and depression in young people with bipolar disorder.  Journal of Affective Disorders. 2012 Dec 20;143:196-202. Link

2. Proudfoot J, Parker G, Manicavasagar V, Hadzi-Pavlovic D, Whitton AE, Nicholas J, Smith M. Effects of adjunctive peer support on perceptions of illness control and understanding in an online psychoeducation program for bipolar disorder: A randomized controlled trial.  Journal of Affective Disorders. 2012 Dec 15;142:98-105. Link

1. Proudfoot J, Parker G, Hadzi-Pavlovic D, Manicavasagar V, Adler E, Whitton AE.  Community attitudes to the appropriation of mobile phones for monitoring and managing depression, anxiety and stress.  Journal of Medical Internet Research. 2010 Dec 19;12:e64. Link